diff --git a/README.md b/README.md index 4acf11328cb9db5a938f983d6076b8e2112119af..d933dec7e7e30276a825e56604436adcba66604f 100644 --- a/README.md +++ b/README.md @@ -1,3 +1,10 @@ + +## Challenge + + +## Links for Srugical Masks, N95, Respirators etc +- https://www.fda.gov/medical-devices/personal-protective-equipment-infection-control/n95-respirators-and-surgical-masks-face-masks + ## Electrospinning Apparatus ### System Components & Process Parameters - Syringe Pump diff --git a/index.html b/index.html index 77bc8cfa0f9e8da3ed2eb9bd65ea5756cbf2455d..b3d706d861b19b3796aad21b4092097dab883dd7 100644 --- a/index.html +++ b/index.html @@ -78,45 +78,69 @@ <h2>A. Filters: Design Specs</h2> <br> - <p class ="lead text-justify"> - 1. ISO fittings to mate with the tubing.<br> - 2. Filtration Efficiency for Covid19. <br> - 3. Low Resistance to flow.<br> - - We will have to trade off specifications for Rqmts 2 and 3. - If the filter is too restrictive, the patient has to work too hard to breath. - It meets the resistance by increasing the surface area, you will have a successful design. + + <p class="lead text-justify"> + We aim to rapidly fabricate membranous filter media against the COVID-19 virus while minimising + breathing resistance in respiratory applications. + Our design goals are to maximise COVID-19 filtration efficiency and minimize pressure drop (air flow + resistance) across the membrane so that the patient doesn't have to work too hard to breath. <br> - <a href = "https://gitlab.cba.mit.edu/camblackburn/filter_testing#fn2-7883" class="text-primary" class="nav-link"> Filter Testing Metrics from Camron</a> + <a href="https://gitlab.cba.mit.edu/camblackburn/filter_testing#fn2-7883" class="text-primary" + class="nav-link"> Filter Testing Metrics from Camron</a> </p> + <p class="lead text-justify"> - Press here for link to: <a href="https://www.intersurgical.com/products/airway-management/floguard-low-resistance-breathing-filter-for-cpap-and-bilevel#downloads" - class="text-primary" class="nav-link"> - Commercial Flo-Guard Breathing Filters</a> + Commercial respiratory filter media that meet regulatory metrics are linked HERE: <a + href="https://www.intersurgical.com/products/airway-management/floguard-low-resistance-breathing-filter-for-cpap-and-bilevel#downloads" + class="text-primary" class="nav-link"> + Commercial Flo-Guard Breathing Filters</a>. </p> - <br> + <br> <img src="img/comm-filter.PNG" class="rounded mx-auto d-block" width="70%"> <br> + + <p class="lead text-justify"> + Commerical respiratory filters are made from these materials...... + </p> + <br> <img src="img/filter-open.PNG" class="rounded mx-auto d-block" width="40%"> <br> - <h4 class='text-sm-center'>Proposed Workflow for Filter Media Production:</h4> - <img src="img/filter-es-production.PNG" class="rounded mx-auto d-block" width="90%"> - <br> + + <p class="lead text-justify"> + Specific design goals metrics are listed below.... These are based on .... + </p> + <hr> <h2>B. Process: Electrospinning</h2> <br> + <p class="lead text-justify"> - The Electrospinning process is based on the electrohydrodynamics phenomenon, where a material - substrate loaded within a syringe with a charged needle tip attached to it and pointing towards - a grounded collector, is extruded and subsequenlly stretched using a high volatage potential. - Assuming that the material substrate is viscoelastic enoough and as soon as the electrostatic stresses - overcome the surface tension of the material, fibers in a chaotic motion are deposited on the collector. + To adress a possible outage of commercial respiratory filters due ot the CVD pandemic, we propose the + design of machines for the production of nonwoven fibrous + membranes made from inorgancic polymer composites with the electrospinning process. Electrospun + membranes can be employed as antiviral filter respiratory media + in protective equipment against the CVD-19 virus. The benefits of electrospun membranes over + conventional filter media media are:...... + The electrospinning process is simple... The challenge is throughput... + but is solvable... explain why... + </p> + + <img src="img/filter-es-production.PNG" class="rounded mx-auto d-block" width="90%"> + <br> + <p class="lead text-justify"> + The electrospinning process is based on the electrohydrodynamics phenomenon, where a material + substrate loaded within a syringe with a charged needle tip attached to it and pointing towards + a grounded collector, is extruded and subsequenlly stretched using a high volatage potential. + Assuming that the material substrate is viscoelastic enoough and as soon as the electrostatic + stresses + overcome the surface tension of the material, fibers in a chaotic motion are deposited on the + collector. The fiber formation mechanism is shown in the video below: </p> - + <video width="800" height="600" style="display:block; margin: 0 auto;" controls> <source src="img/electrospinning-amazing-video-smaller.mp4" type="video/mp4"> </video> @@ -124,40 +148,69 @@ <p class="lead text-justify"> The two main types of electrospinning process are: a) solution electrospinning (SES) and b) melt - electrospinning (MES). This classification is based on the material form used for processing; with SES using - a polymer solution (pellets/powder mixed with solvent) and MES using pure polymer melt without any chemical solvents. - The 3 main common system components for both process types are: a) the extrusion device that can be either - mechanical using a syringe pump or pneumatic, b) a high-voltage power supply and c) a collector that in + electrospinning (MES). This classification is based on the material form used for processing; with + SES using + a polymer solution (pellets/powder mixed with solvent) and MES using pure polymer melt without any + chemical solvents. + The 3 main common system components for both process types are: a) the extrusion device that can be + either + mechanical using a syringe pump or pneumatic, b) a high-voltage power supply and c) a collector that + in the most basic setup is a flat grounded aluminum plate. </p> <br> <img src="img/ses-vs-mes.PNG" class="rounded mx-auto d-block" width="80%"> <br> + <p class="lead text-justify"> - Different types of nozzles and collectors assembled either in a horizontal or vertical configuarations have been - reported in the literature leading to different types of electrospinning processes. Each electrospinning process + Different types of nozzles and collectors assembled either in a horizontal or vertical + configuarations have been + reported in the literature leading to different types of electrospinning processes. Each + electrospinning process has advantages and disadvantages depending on the application. </p> <hr> - <h2>C. What is the best type of electrospinning process for rapid diy breathing filter media production? + <h2>C. Which is the most suitable type of electrospinning process for repsiratory folter media production? </h2> + <p class="lead text-justify"> + ENM can be potentially employed to filter a variety of pollutants. ENM can capture PM due to a + combination of small diameter, + small pore size and high specific surface area. Moreover, the surface of ENM can be functionalized + to adsorb different VOCs. + Electrospun nanofibres can also be engineered to reduce the pressure drop which is immensely + desirable for respiratory filter media. + Carefully engineered ENMs can simultaneously extract harmful aerosols and gases from the air with + minimum air resistance. + This hypothesis is tested in various experiments involving different approaches, viz. beaded + nanofibres, bilayer nanofibres, use of + specific additives, and surface modification of electrospun nanofibres. This research is aimed at + studying ENM as a protective material + against different air pollutants while minimising breathing resistance in respiratory applications + with the following objectives: + [1] To reduce pressure drop (air resistance) across the ENM while maximising PM filtration + efficiency; + </p> + <p class="lead text-justify"> - high-throughput<br> - - multiple nozzles<br> - - rolling collector<br> + - multiple nozzles<br> + - rolling collector<br> - polymer solution for functionalization<br> - - hydrophobicity<br> - - anti-viral material<br> + - hydrophobicity<br> + - anti-viral material<br> - fast cheap assembly<br> </p> <p class="lead text-justify"> - Below in Section "D" we propose 3 different types of electrospinning machines of varying complexity and capabilities staring - from the simplest one that can be made with off-the0shelf components that might be laying around in a hospital, moving to a - simple design that reducing the cost, is parallelizable and can be made in a fab lab using a laser cutter and a 3D printer and + Below in Section "D" we propose 3 different types of electrospinning machines of varying complexity + and capabilities staring + from the simplest one that can be made with off-the0shelf components that might be laying around in + a hospital, moving to a + simple design that reducing the cost, is parallelizable and can be made in a fab lab using a laser + cutter and a 3D printer and resulting to a slightly more advanced for increaed throughput. </p> @@ -210,8 +263,6 @@ <h2 class="text-sm-center" id="fabes4">FAB-ES Machine #4</h2> <h4 class="text-sm-center" id="fabes4">Roll-to-Roll Blowing Electrospinning</h4> - - </div> </div> </div>